Citra-Lock™ S (trisodium citrate)

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Therapy area 

Citra-Lock™ S (trisodium citrate): Anticoagulant and Antimicrobial catheter lock solution to help maintain catheter patency and reduce catheter related infections. The range of pre-filled syringes contain trisodium citrate locking solution available in 4%, 30% & 46.7%.

Trisodium Citrate 4% is an alternative to Heparin1,2

Citra-Lock™ 30% and 46.7% significantly reduces the amount of Urokinase used in haemodialysis units3,4

Citra-Lock™ 30% has been shown to work more effectively than TauroLock™/ Heparin solution in maintaining effective blood flow rates4

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References:

  1. Yon C K et al, Sodium citrate 4% versus heparin as a lock solution in hemodialysis patients with central venous catheters, Am J Health-Syst Pharm- Vol 70 Jan 15, 2013
  2. Lok C E et al, Trisodium citrate 4% - an alternative to heparin capping of haemodialysis catheters, Nephrol Dial Transplant (2007) 22: 477-483 doi: 10.1093/ndt/gfl 570, Oct 2006
  3. Legaac R, Catheter Care Management in Haemodialysis, European Nephrology, 2011;5(2):138–42
  4. Sanchez R & Dean S, Our experience using Citra-Lock™ 30% to maintain the patency of permanent tunnelled vascular catheter, poster at BRS 2012
Adverse events should be reported. Reporting forms and information can be found at https://yellowcard.mhra.gov.uk/. Adverse events should also be reported to Syner-Med (Pharmaceutical Products) Limited. Tel. +44 020 8655 6380

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