Hyacyst® (sodium hyaluronate)

Product category 

Therapy area 

  • Urology
  • Gynaecology

Hyacyst® (sodium hyaluronate) is a bladder instillation indicated for the temporary replenishment of the GAG layer in the following bladder conditions; interstitial cystitis (IC), painful bladder syndrome (PBS), haemorrhagic cystitis, recurrent bacterial cystitis, radiation induced cystitis and chemotherapy induced cystitis.

Hyacyst® (sodium hyaluronate) is available in strengths of 40mg/50ml and 120mg/50ml which are supplied as Pre-Filled Syringes (PFS). Hyacyst® PFS packs include a catheter adaptor to enable Hyacyst® PFS to be used with a wide variety of available catheters, making them suitable for self-instillation at home.

Hyacyst® (sodium hyaluronate) is approved for prescribing in the Community on FP10 prescriptions in the UK.

Hyacyst® (sodium hyaluronate) 40 PFS was the first 40mg/50ml sodium hyaluronate bladder instillation in a pre-filled syringe.

Hyacyst® (sodium hyaluronate) 120 PFS is a higher dose option when increased replenishment of the GAG layer is required.

In a 2014 randomised study, Hyacyst® (sodium hyaluronate) 120mg/50ml was proven to be as effective as combination treatment iAluRil® (sodium hyaluronate, sodium chondroitin sulfate and calcium chloride) in reducing symptoms in patients with IC/PBS1.



  1. Gülpinar O et al. Clinical comparison of intravesical hyaluronic acid and hyaluronic acid-chondroitin sulphate therapy for patients with bladder pain syndrome/interstitial cystitis. Can Urol Assoc J 2014;8(9-10):e610-4’
Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard. Adverse events should also be reported to Syner-Med (Pharmaceutical Products) Limited. Tel. +44 020 8655 6380

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